A female cat (queen) is capable of producing several litters of kittens every year throughout her life. If you don't want to take on the responsibility of finding good homes for the kittens you should have your queen neutered. Keeping an un-neutered queen indoors is not a good answer to the problem. A calling queen will keep you and your neighbours awake and will do her best to escape at every opportunity. There is also a risk of infection developing in your cat's uterus (pyometra) if she is neither neutered or bred from and cancer of the mammary gland (breast cancer) is more common in un-neutered cats. If you do decide to breed from your cat there are various things to consider to make sure that both mother and kittens are strong and healthy.